Nurse Practitioners pay in St. Louis

In St. Louis (MO), the median pay for nurse practitioners is $63.26 an hour ($131,580 a year). About 3,430 people work in this job there.

$63.26Median hourly pay
$127,460–$154,500Middle half of workers, yearly
3,430People in this job in St. Louis (MO)

That is about the same as the U.S. median ($132,300). It is about the same as the Missouri median ($129,930).

Pay range for nurse practitioners in St. Louis (MO)

Earns more thanHourlyYearly
10% of workers$52.09$108,340
25% of workers$61.28$127,460
Half of workers (median)$63.26$131,580
75% of workers$74.28$154,500
90% of workers$78.98$164,280

Nurse Practitioners pay in Missouri metro areas

Metro areaMedian yearly payPeople in this job
St. Louis (this page)$131,5803,430
Kansas City$130,7602,730
Cape Girardeau$130,000200
Columbia$128,930330
Jefferson City$128,710130
St. Joseph$128,710140
Joplin$126,640230
Springfield$125,630660

Missouri unemployment rate: 3.5% (August 2026), U.S. Bureau of Labor Statistics.

Education, experience and outlook for nurse practitioners

  • Typical education to start: Master's degree (BLS)
  • Related work experience most have: 1 to 2 years (O*NET)
  • Job outlook: +41% over ten years, much faster than average · about 29,400 openings a year (BLS)

Related jobs in St. Louis (MO)

JobMedian yearly pay
Registered Nurses$83,180
Paramedics$63,050
Family Medicine Physicians$76,830
Physician Assistants$136,120
Pharmacists$138,530
Physical Therapists$100,600
Occupational Therapists$95,770
Speech-Language Pathologists$86,480

Other job titles for this job

NPAcnpAdult Nurse PractitionerAdvanced Practice NurseAdvanced Practice Registered NurseAprnArnp SpecialistCardiology Nurse PractitionerCertified Nurse PractitionerCertified Registered Nurse PractitionerCPNPDermatology Nurse Practitioner

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Source: U.S. Bureau of Labor Statistics, Occupational Employment and Wage Statistics (OEWS), May 2025 estimates. Figures are for wage and salary workers and do not include the self-employed. The median is the middle wage: half earn more, half earn less. Other job titles: O*NET 31.0 Database by the U.S. Department of Labor, Employment and Training Administration (USDOL/ETA), used under the CC BY 4.0 license; O*NET® is a trademark of USDOL/ETA. JAI Bot has modified this information; USDOL/ETA has not approved, endorsed, or tested these modifications.