Physician Assistants pay in St. Louis

In St. Louis (MO), the median pay for physician assistants is $65.44 an hour ($136,120 a year). About 1,260 people work in this job there.

$65.44Median hourly pay
$124,080–$164,700Middle half of workers, yearly
1,260People in this job in St. Louis (MO)

That is about the same as the U.S. median ($135,880). It is about the same as the Missouri median ($135,130).

Pay range for physician assistants in St. Louis (MO)

Earns more thanHourlyYearly
10% of workers$37.32$77,620
25% of workers$59.65$124,080
Half of workers (median)$65.44$136,120
75% of workers$79.18$164,700
90% of workers$82.19$170,960

Physician Assistants pay in Missouri metro areas

Metro areaMedian yearly payPeople in this job
Joplin$150,30070
Cape Girardeau$141,08040
St. Joseph$138,06050
St. Louis (this page)$136,1201,260
Jefferson City$135,34040
Kansas City$133,350540
Columbia$132,220140
Springfield$129,270300

Missouri unemployment rate: 3.5% (August 2026), U.S. Bureau of Labor Statistics.

Education, experience and outlook for physician assistants

  • Typical education to start: Master's degree (BLS)
  • Related work experience most have: 6 months to 1 year (O*NET)
  • Job outlook: +21.1% over ten years, much faster than average · about 11,500 openings a year (BLS)

Related jobs in St. Louis (MO)

JobMedian yearly pay
Registered Nurses$83,180
Nurse Practitioners$131,580
Family Medicine Physicians$76,830
Pharmacists$138,530
Physical Therapists$100,600
Occupational Therapists$95,770
Speech-Language Pathologists$86,480
Respiratory Therapists$79,210

Other job titles for this job

AapAnesthetic AssistantCardiology Physician AssistantCertified Physician AssistantPa-cCertified Physician S AssistantEmergency Medicine Physician AssistantEmergency Medicine PaFamily Medicine PaFamily Physician AssistantFamily Practice Physician AssistantGynecological Assistant

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Source: U.S. Bureau of Labor Statistics, Occupational Employment and Wage Statistics (OEWS), May 2025 estimates. Figures are for wage and salary workers and do not include the self-employed. The median is the middle wage: half earn more, half earn less. Other job titles: O*NET 31.0 Database by the U.S. Department of Labor, Employment and Training Administration (USDOL/ETA), used under the CC BY 4.0 license; O*NET® is a trademark of USDOL/ETA. JAI Bot has modified this information; USDOL/ETA has not approved, endorsed, or tested these modifications.